{"title":"Wellness","description":"","products":[{"product_id":"nad","title":"NAD+","description":"\u003ch2 data-path-to-node=\"2\"\u003eVitality NAD+ (Nicotinamide Adenine Dinucleotide)\u003c\/h2\u003e\n\u003cp data-path-to-node=\"3\"\u003eA specialized coenzyme formulation supplied in a pre-filled research device, provided exclusively for controlled laboratory R\u0026amp;D applications. Delivered in a sealed format to support cellular energy analysis, mitochondrial stability studies, and metabolic pathway evaluation.\u003c\/p\u003e\n\u003cp data-path-to-node=\"4\"\u003e\u003cb data-path-to-node=\"4\" data-index-in-node=\"0\"\u003eProduced for laboratory research only. Not for human or veterinary consumption.\u003c\/b\u003e\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"5\"\u003eEach Vitality Research kit includes:\u003c\/h3\u003e\n\u003cul data-path-to-node=\"6\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,0,0\"\u003e\u003cb data-path-to-node=\"6,0,0\" data-index-in-node=\"0\"\u003ePre-filled Research pen\u003c\/b\u003e (Total concentration specified per unit)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,1,0\"\u003e\u003cb data-path-to-node=\"6,1,0\" data-index-in-node=\"0\"\u003eResearch information sheet\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,2,0\"\u003e\u003cb data-path-to-node=\"6,2,0\" data-index-in-node=\"0\"\u003eStorage:\u003c\/b\u003e Store refrigerated (2–8°C). Do not freeze. Protect from light. Supplied in a fixed-volume sealed format for laboratory analysis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"6,3,0\"\u003e\u003cb data-path-to-node=\"6,3,0\" data-index-in-node=\"0\"\u003eDelivery:\u003c\/b\u003e Dispatched with a cold pack. Tracked 2 DAY UK Delivery. Research \u0026amp; Development purposes only.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"8\"\u003eScience \u0026amp; Mechanism: What is this compound?\u003c\/h2\u003e\n\u003cp data-path-to-node=\"9\"\u003eIn a laboratory environment, Nicotinamide Adenine Dinucleotide (NAD+) is a highly critical coenzyme found in all living cells. It serves as a foundational element for cellular respiration, metabolic function, and DNA maintenance. Because systemic levels naturally decline with cellular senescence, this formulation is widely utilized in longevity, neurological, and metabolic R\u0026amp;D to evaluate cellular rejuvenation and energetic optimization.\u003c\/p\u003e\n\u003cp data-path-to-node=\"10\"\u003eHere is how the compound behaves in a research setting:\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"11\"\u003e1. Mitochondrial Optimization \u0026amp; ATP Production\u003c\/h3\u003e\n\u003cul data-path-to-node=\"12\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,0,0\"\u003e\u003cb data-path-to-node=\"12,0,0\" data-index-in-node=\"0\"\u003eThe Cellular Powerhouse:\u003c\/b\u003e NAD+ acts as a primary electron transporter in the electron transport chain. In vitro studies focus on its ability to transition between its oxidized (NAD+) and reduced (NADH) states, which is essential for generating adenosine triphosphate (ATP)—the fundamental energy currency of the cell.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,1,0\"\u003e\u003cb data-path-to-node=\"12,1,0\" data-index-in-node=\"0\"\u003eMetabolic Homeostasis:\u003c\/b\u003e Researchers use NAD+ to observe its role in glycolytic and citric acid cycle pathways, crucial for maintaining balanced cellular metabolism.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"13\"\u003e2. Sirtuin Activation (The \"Longevity\" Pathways)\u003c\/h3\u003e\n\u003cul data-path-to-node=\"14\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,0,0\"\u003e\u003cb data-path-to-node=\"14,0,0\" data-index-in-node=\"0\"\u003eEpigenetic Regulation:\u003c\/b\u003e NAD+ is an obligate co-substrate for sirtuins (specifically SIRT1 and SIRT3), a class of proteins linked to cellular lifespan, mitochondrial biogenesis, and regulation of oxidative stress.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"14,1,0\"\u003e\u003cb data-path-to-node=\"14,1,0\" data-index-in-node=\"0\"\u003eCaloric Restriction Mimicry:\u003c\/b\u003e In laboratory models, robust NAD+ availability activates these sirtuin pathways, mimicking the cellular defense mechanisms typically triggered by fasting or caloric restriction.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"15\"\u003e3. DNA Repair \u0026amp; PARP Activation\u003c\/h3\u003e\n\u003cul data-path-to-node=\"16\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"16,0,0\"\u003e\u003cb data-path-to-node=\"16,0,0\" data-index-in-node=\"0\"\u003eGenomic Stability:\u003c\/b\u003e NAD+ is consumed by PARP (Poly ADP-ribose polymerase) enzymes, which detect and initiate the repair of damaged DNA strands.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"16,1,0\"\u003e\u003cb data-path-to-node=\"16,1,0\" data-index-in-node=\"0\"\u003eCellular Resilience:\u003c\/b\u003e Assays demonstrate that maintaining optimal NAD+ levels allows cells to effectively counter genomic instability, environmental stressors, and programmed cell death (apoptosis).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"18\"\u003eWhy this compound is valuable for R\u0026amp;D\u003c\/h2\u003e\n\u003cp data-path-to-node=\"19\"\u003eNAD+ is an indispensable asset for researchers investigating the core mechanisms of cellular aging, mitochondrial decay, and metabolic dysfunction. Because it simultaneously drives energy production while fueling the enzymes responsible for DNA repair and cellular survival (PARPs and Sirtuins), it offers a dual-action mechanism. This makes it an incredibly robust mono-formulation for studies centered on neuroprotection, age-decline reversal, and systemic metabolic resilience.\u003c\/p\u003e","brand":"Telos Life","offers":[{"title":"Default Title","offer_id":62746442924362,"sku":null,"price":120.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1058\/2202\/8106\/files\/imgi_4_NAD-1000mg.jpg?v=1784244475"}],"url":"https:\/\/teloslife.co.uk\/collections\/wellness.oembed","provider":"Telos Life","version":"1.0","type":"link"}